Latest News and Developments about Humankind's Drive Towards Biological Immortality

What is a hormone?

Hormones are chemical substances that are discharged by a single or more than a cell, and these chemicals influence other cells in organism. To modify the metabolism of a cell an insignificant quantity of hormone is enough. Besides, hormones act as chemical messengers that transmit signals from cell to cell.

Yet, hormones are present in all forms of organisms. Phytohormones are those for plants. The hormones present in mammals are transmitted in the blood. All cell specific responses in relation to hormone are triggered by transduction mechanism with receptor protein that connects to particular hormones. Different hormones have alternative roles. In the body some common hormones are reproductive hormones, HGH, thyroid hormones, DHEA, pituitary hormones, adrenal hormones to mention a few.

Hormone & Aging

It is a fact that hormone levels start to decline with age. Around the age of 20, hormone levels begins to shrink, this include DHEA, Melatonin, pregnenealone, testosterone and HGH (Human Growth Hormone). HGH is practically reduced by around 80 percent in individuals from the age of 20 to 60. Significant fall in hormone levels has repercussions such as degenerative effects on immune system functioning. Researchers believe that a fall in the hormone level has a major contribution to aging.

It is quite simple to understand the aging related theory. As the level of hormone declines the mechanisms, that they were supposed to control do also experience the same fall. Our biological processes are heavily dependent on hormones, as the immune system just mentioned, and are consequently deprived. Even gene transcriptions are influenced by the composition of hormones. The real impact can be experienced in alteration in endurance, mental acuity, energy level, resistance to diseases, bone-loss related to age, metabolism & weight, and sleeping abilities.

Some of the particular diseases that are connected with hormone deficiencies are, exotic sounding disease which is connected with testosterone deficiency causing hypospadias and cryptorchidism, as well as testicular cancer.

Hormone composition in the body of male and female tends to influence personality and attributes of people. Internal body processes are also influenced by hormone like acids and prostaglandins. They have a tendency to vary metabolism and body temperature as well as preventing immune cells to perform their task with age. Research says that modification in prostaglandins is more sensitive to elder people and thus likely an origin of immune deficiency for aged individuals.

Hormone level decline in older people does even decrease osteoporosis and bone density. This reduction is responsible for major physical age-related predicaments such as falling injuries and having difficulties to move. The fading of key hormones lead to hyperinsulinemia but the latter is more precisely affected by insulin resistance. The presence of hyperinsulinemia brings about common old-age diseases such as Alzheimer’s disease and cardiovascular diseases.

Protecting or Firewall against Decline in Hormone Levels Firewall
1. Lifestyle

The mood of living contributes to maintain and control the levels of hormones. The focus is on constant exercise. For example during a day, around 30 to 45 minutes should be spent to perform light cardiovascular exercise, which can include swimming, walking, gardening amidst other yard works. Mental exercises are also vital such as reading, learning or writing. To avert all major health predicaments, it is recommended to have regular and constant sleep as well as a restriction of intake of both alcohol and caffeine.

2. Medical Supplement or Firewalls against decline in hormone levels

The major counterbalancing strategy to tackle decline in hormones is to take supplements which increase the level of hormones at old age. Yet, increasing the hormone levels cannot be done to all hormones present in the body, the most substantial hormones should only be increased. For instance, HGH (Human Growth Hormone) should not be taken as they can contribute to various side effects such as arthritis.

Two substances that can be taken are DHEA and pregnenalone. Pregnenolone is effective as it can transform into many steroid hormones such as estrogen, cortisone, DHEA, progesterone and testosterone. However, the conversion rate to testosterone and estrogen depends on gender. The enhancement that is experienced is reduction in joint pain, better skin conditions and higher cognitive abilities. DHEA is diminished in the body with age. It can be condensed even more through diseases such as diabetes and AIDS or even by the intake of certain drugs. DHEA is, according to research, also appropriate to address depression, adrenal insufficiency as well as systemic lupus erythematosus (SLE).

Other substances:

1. Melatonin – It is a necessary substance to address anti-aging by reinforcing immune system and contributing to better abilities to sleep. It also appears to have a 24-hour circadian rhythm of behavioral, physiological and biochemical processes. For instance, melatonin becomes an important substance for people who travel a lot and have to anticipate time zone changes.

3. Resveratrol – Also used to address anti-aging correlated to bone loss. According to two different studies resveratrol was by one considered able to improve the propagation as well as osteoblastic differentiation of mesenchymal stem cells in humans. Moreover, by another study, resveratrol proved to exhibit protective effects to bones tantamount to hormone replacement therapy.

Study 1:
Study 2:

Furthermore, hormone levels appear to be preventive against various cancers mainly prostate cancer for men and breast cancer for women. According to statistics, 50 percent of prostate cancer cases are linked with gene alteration. The modification to genes helps estrogen- signals to provoke harmful diseases. Here, selenium, zinc, saw palmetto, lycopene and stinging nettle extracts are recommended firewalls to monitor testosterone and estrogen amidst other hormones that are linked.

To tackle insulin resistance,
4. Chromiom piclonate can be taken, and it does even assure weight control and elimination of extra insulin.

5. DHEA, CoQ10, L-carnosine, Vitamin C and E, alpha-lipoic acid and magnesium are all firewalls that eliminate excess insulin while addressing glycation and weight control.

The firewalls used to tackle declines in hormone levels are also used to take action against other aging-theories. This makes it vital to understand the multi-purpose of these firewall substances across all anti-aging theories.

Reference
1. Hormone levels
2. Hormone
3. Anti- aging firewalls the science and technology of longevity.

Anti Aging, Anti Aging Supplements, Anti Aging Theories, Health And Aging, Lifestyle