Cell DNA damage is devastating to longevity and generally the cause of many diseases. The first thing that we should understand is what DNA is. DNA is the acronym for Deoxyribonucleic acid and is a nucleic acid that holds the secret of genetic attributes that determine the overall functioning of all living organisms.
Yet, DNA damage to cells can be caused by mainly two ways: DNA damage and Mutation. Cell DNA damage is a physical abnormality present in DNA. Damage caused to cell DNA can be identified by enzymes, implying that damaged cells can be repaired if sufficient information is available. For instance, information about cells that are similar to the damaged cells will enable a copy to be made. Nonetheless, cell DNA damage might eventually kill a cell as the protein and replication capabilities of the cell become inhibited.
Moreover, DNA damage caused by mutation does ultimately alter the DNA sequence. DNA damage caused by mutation cannot be identified by enzymes and is at current state of technology impossible to repair once totally mutated. Mutation at the cellular level changes the function of protein. The mutated cells will afterward spread as they replicate through cell division. Yet, the mutant cell can either expand or slowly decrease depending on its replication and survival abilities.
Cell DNA Damage and mutations is a major cause of age-related diseases. For instance, oxidative damage can cause damage to a cell’s DNA. Oxidative damage can evolve from toxic environments, smoking as well as from some anti-inflammatory and antibiotics medicine. The general effect of the harm caused to the cell is seen in the cell’s ability to replicate, apoptosis, production of abnormal tissues, creating of cancer and premature senescence cells.
The possible illnesses related to genetic break/Cell DNA damage are abundant. To mention a few we have, arteriosclerosis, neuro-degenerative diseases, Alzheimer’s and Parkinsons’s diseases, any type of cancer, immunodeficiency, rheumatoid arthritis, chronic fatigue and diseases.
DNA mutation theory of aging is not solely based on oxidative damage. It is congruent to other theories of aging as well.
Protecting against Cell DNA Damage
1. Lifestyle
A healthy lifestyle goes beyond simply dietary to avoiding exposure to microwaves or x-radiations that might provoke free radicals (ROS) in the human body. Some basic measure is to avoid becoming an active and passive smoker. One has to stay protected from direct sun exposure by using sunglasses and proper clothes. The use of toxic chemical should be handled with due care, for example arsenic-containers should not be handled without gloves.
A dietary habit is another necessary approach to supply the body with sufficient sources of fresh energy. Consumption of fruits, vegetables some fish should be made a priority with a regulated intake of red meat, trans-fatty acids and omega-6-fatty. Food should be cooked at reasonable temperature to prevent brownness. Moreover, food in mercury containers such as tuna should be consumed, at a recommended rate of one per week. Foods that should be avoided are fast food, fried-food, food preserved in nitrites and hydrogenated oils. On the other hand, broccoli, sardines, blueberries, olive oil, green tea are advised to be consumed plenty. Dark chocolate with a density of cacao content is also recommended, while alcohol (Red Wine) can be drunk moderately to de-stress.
2. Medical Supplement/ Firewalls against Cell DNA Damage
To regulate genes that are responsible for the control of apoptosis, cell cycle arrest and inhibition of cell growth, maintaining the health state of the cell, green tea, ashwagandha, curcumin and resveratrol should be consumed. It is only lately that the importance of these herbal ingredients has been identified. They play a primordial role in installing firewalls to prevent cancers. Furthermore, resveratrol, a polyphenol that is present in the skin of grapes and by virtue in red-wine does eventually create a genetic reaction that extends life for both plants and animals. Life of mainly small sized animals can experience a substantial increase in life span by as much as 30 percent. It believed that other polyphenols such as OPC could have alike results.
Moreover, in Programmed Genetic Change, the 13th theory of aging substances such as Alpha-lipoic acid amidst other compositions helps to stop the activation of the nuclear factor NF-kappaB that thereby protects DNA. Some of the positive benefits of this inhibition are that it can lower risk of atherosclerosis or diabetes and prevent skin from wrinkling.
Cell DNA Damage can be prevented to a great deal by using the protective firewalls prescribed. Yet, other causes of aging can still prevail.
ANTI-AGING FIREWALLS THE SCIENCE AND TECHNOLOGY OF LONGEVITY
DNA damage and mutation
Mon, Dec 14, 2009
Anti Aging Theories, Health And Aging, Lifestyle, Longevity