Attaining an appropriate balance of proteins in what we eat may well be more significant to our aging health than decreasing our calorie intake according to some recent research.
The investigation could also help determine why caloric restriction or dietary restriction, basically cutting back on calories while maintaining adequate levels of all nutrients, seems to have added benefits for our physical condition and aging process. It has already been proven that various organisms will live longer on a restricted diet and some animals also respond by living longer as well. There has been confirmation that humans can also enjoy some benefits from caloric restriction, however, the jury is still out as to whether it can lead to a longer life for humans.
Caloric limitation may also have an unconstructive adverse effect and that would be lowered fertility. For instance, the fruit fly will have fewer offspring when on a calorie reduced diet and the number of progeny are also reduced – however – the reproductive period remains longer. Researchers credit this to an evolved characteristic that derived from periods of famine some necessary nutrients are sidetracked away from replication in order to aid in survival of the organism.
In order to determine the specific benefits of restricting diet, if the advantages came from decreases in particular elements or just the process of reducing calories, scientists calculated the results when manipulating the food intake of female fruit flies.
Those fruit flies consumed a diet consisting of yeast, sugar and water, though it contained differing quantities of important nutrients like vitamins, lipids and amino acids. Study techs noticed that changing the levels of amino acids in the concoction had an effect on the life span and their fertility; doing the same for the other elements did not have any impact.
In addition, upon closer observation they saw that quantities of a certain amino acid called methionine were vital toward maximizing longevity while not reducing fertility patterns. Including methionine into a calorie limited diet enhanced fertility while maintaining longevity. At the same time, decreasing methionine levels in high caloric diets actually extended life spans. Earlier studies had already displayed that lowered levels of methionine in mice and rats assisted in prolonging life expectancy.
When the amounts of amino acids are vigilantly juggled in a diet scientists actually were able to maximize the life expectancy and fertility patterns in test organisms. The study clearly shows that the possibility exists to increase life expectancy while not widely reducing caloric intake and also not interfering with the important cycle of reproduction.
Amino acids makeup the basis of the creation of life as they aid in creating proteins. Methionine is a very significant amino acids in the formulation of each protein. As proteins are created in the body innately, so too are they consumed in the foods we eat like red meats, dairy and soy products like tofu. The proliferation of methionine varies according to what type of food is ingested and is naturally occurring in sesame seeds, brazil nuts, wheat germ, fish and meat in larger amounts.
Previous science has led us to believe that protein quantity intake was imperative for us in our diet but in the fruit fly examination, it has been shown the amino acid balance in a diet is vital towards our health as we age, and this is probably the same scenario for other forms of life. If humans were indeed part of this development, the kind of protein then becomes additionally noteworthy.
We cannot just simply say we should eat fewer nuts or consume more nuts so we will live longer; it boils down to finding the correct balance of protein in the diet. This aspect could be specifically significant in a high protein diet like the Atkins diet or heavily protein laden diets of body builder and their protein supplementation regimens.
Since the effectual outcome of caloric limitation on life expectancy seems to have to do with species advancement, as it happens in organisms from yeast to rhesus monkeys, researchers think that the method could also be preserved. This opens the up the idea of exploiting the organism models to investigation regarding the mechanics of food limitation and how actually functions.
Since the human DNA structure has approximately four times the amount of genes as the fruit fly genome does, there are still a number of closely related similarities amongst these genes. Given the fact, it is so easy to produce altered organisms for the experimentation with fruit flies, the functionality of many of the fly’s genes has been established, and recently discovered human genes can be compared to their fruit fly doppelganger. Consequently, even though the fruit fly seemingly does not resemble humans, numerous discoveries regarding its fundamental biology can be interpreted into human biology.


Fri, Jan 1, 2010
Anti Aging, Bioscience, Longevity